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AIVD - the world's leading supplier of IVD raw materials

 

AIVD Biotech has established three R&D divisions: IVD Raw Materials, Immunodiagnostic and Molecular Diagnostic Test Kit.

 

The IVD raw material division includes antigen R&D center and antibody R&D center, while the antigen R&D center includes two expression platforms: prokaryotic (E. coli) and eukaryotic (Baker's yeast, CHO cells, 293T cells); the antibody R&D center includes hybridoma cell fermentation and recombinant antibody (nano-antibody) production platforms.

 

AIVD Biotech is professional in providing in vitro diagnostic test kit overall technical solutions, accepting orders for custom development and production of diagnostic raw materials and custom development and production of diagnostic test kits, full chain technology transfer, etc. Welcome to inquire.

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The colloidal gold immunochromatography assay combines antigen-antibody immune reaction and colloidal gold labeling technology for qualitative and quantitative detection of antigen and antibody content. This assay has been widely used in the field of clinical diagnosis due to its multiple advantages such as rapidness, simplicity, low cost, and good stability.
Fluorescence immunochromatography assay is a new type of membrane detection technology based on antigen-antibody specific immune response. The technology uses a strip of fiber chromatography material immobilized with a detection line (coated antibody or coated antigen) and a quality control line (anti-antibody) as the stationary phase, the test solution as the mobile phase, and the fluorescently labeled antibody or antigen is immobilized on the connection pad , which moves the analyte on the strip by capillary action.
Chemiluminescence immunoassay (CLIA) is an assay that combine chemiluminescence technique with immunochemical reactions. Similar with other labeled immunoassays (RIA, FIA, ELISA), CLIA utilize chemical probes which could generate light emission through chemical reaction to label the antibody. In recent years, CLIA has gained increasing attention in different fields, including life science, clinical diagnosis, environmental monitoring, food safety and pharmaceutical analysis because of its high sensitivity, good specificity, wide range of applications, simple equipment and wide linear range.
ELISA (enzyme-linked immunosorbent assay) is a plate-based assay technique designed for detecting and quantifying soluble substances such as peptides, proteins, antibodies, and hormones. Other names, such as enzyme immunoassay (EIA), are also used to describe the same technology. In an ELISA, the antigen (target macromolecule) is immobilized on a solid surface (microplate) and then complexed with an antibody that is linked to a reporter enzyme. Detection is accomplished by measuring the activity of the reporter enzyme via incubation with the appropriate substrate to produce a measurable product. The most crucial element of an ELISA is a highly specific antibody-antigen interaction.
The "latex" immunochromatographic method actually refers to colored latex particles as tracer markers, specifically the latex lateral chromatographic immunochromatographic method. Colored latex is nanoscale homogeneous latex particles, the surface of which can be modified with carboxyl, amino or other chemical groups as needed, through which proteins can be coupled with latex particles and form a stable bond. Lateral chromatography immunoassay products that use latex particles coupled with specific antigens or antibodies are referred to as latex-based rapid assays.
Turbidimetric immunoassay, also known as immunoturbidimetry or turbidimetry, is based on measuring the turbidity of a sample to determine the level of an analyte. This method is commonly used to quantify antigen-antibody complexes. The formation of antigen-antibody complex increases the turbidity of the sample. When light passes through the reaction solution, part of the light is scattered by the sample, part of the light is absorbed by the sample, and the rest of the light passes through the sample. The concentration of protein antigen in the sample is determined by measuring the absorbance of light from a sample. This assay has been widely used in clinical diagnosis, e.g., measurement of PAI-1 and serum C-reactive protein (CRP).
The platform utilizes the hybridization principle of nucleic acid and corresponding nucleic acid, and uses special nucleic acid as a probe to effectively detect specific sequences in somatic cells or nucleic acids. It has built detection platforms such as fluorescence quantitative PCR and next-generation sequencing, and can provide customers with qPCR Raw materials, high-throughput sequencing library building reagents, isothermal amplification and other products, and the lyophilization process development of the products, which have excellent performance in substrate specificity, thermal stability, acid-base tolerance range, and specific activity. , stable, meet the needs of molecular biology R&D and production in different scenarios, and help customers realize the industrialization of reagents quickly and conveniently.
Calibration is the foundation of all clinical laboratory testing that insures the accurate reporting of patient results. Calibration is the process that links the analytical signal with the concentration of analyte present in serum, urine or other body fluid. Calibration materials should have the same matrix as patient samples. Serum based calibrators should be used when testing patient plasma or serum, while urine based calibrators should be used for urine chemistry tests. Calibrators should be traceable to standard reference materials to insure comparable and accurate results.
Other types of in vitro diagnostic immunoassay platforms.

Shenzhen AIVD Biotechnology Co. , LTD.

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