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CA72-4
CA72-4 is a tumor marker (TM) that has been found elevated in a variety of human adenocarcinomas, with reported sensitivities of up 50% and overall specificity of over 95%.
Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, lung, and pancreatic cancers. It is a mucin-like molecule with a molar mass of over 1000 kDa.
TAG-72 is a tumor marker measured with radioimmunoassays like CA 72-4, which uses the monoclonal antibodies indium (111In) satumomab pendetide and iodine (125I) minretumomab. This assay has a good specificity for gastric cancer, with a correlation to the neoplasia's extension. It is used to identify relapses of the disease and to follow up the treatment.
TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.
- Product name
- Catalog NO.
- Source
- Usage
- Platform
- CA724 mAb ABC72403
- Catalog NO. ABC72403
- Source CHO
- Usage Coating
- Platform CLIA, ELISA
- CA724 mAb ABC72402
- Catalog NO. ABC72402
- Source CHO
- Usage Coating
- Platform CLIA, ELISA
- CA724 mAb ABC72401
- Catalog NO. ABC72401
- Source CHO
- Usage Labeling
- Platform CLIA, ELISA
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