FIA - Fluorescence Immunochromatography Solutions
Fluorescence immunoassay (FIA) is a simple, rapid, and sensitive technique that is used to quantitevly mesure many compounds including hormones, proteins and drugs. This method has been widely applied in the in vitro diagnostics (IVD) industry.
A modern fluorescent based immunoassay uses as the detection reagent – fluorescent microspores which absorb light or energy (excitation energy) at a specific wavelength and then emits light or energy at a different wavelength.
The FIA test consists of:
1) a conjugate pad containing specific protein (antibody or antigen) conjugated with fluorescent microspheres (probe conjugate) and a control antibody robe conjugate.
2) a nitrocellulose membrane with immobilized proteins in the test area (T line) and a control line (C line).
After adding the specimen to the sample well on the test cassette, protein in the sample will interact with the probe conjugate on the probe pad. The NC membrane diffuses re-solubilized conjugate forward. As the sample moves along the devise binding reagents situated on the NC membrane bind to the target at the T and C line.
Concentration in specimen is positively correlated with the fluorescent density of the fluorescent microspheres, after the measure and calculation of the quantitative fluorescence immunoassay analyzer, then the analyzer would calculate the concentration according to the preset calibration curve in the machine and display the result. C line should appear in any cases, which indicates the reaction system is effective.
As an expert in IVD assay development, AIVD Biotech is committed to offering a reliable and sensitive FIA-based testing service to accelerate the application of FIA technique in the IVD field.
AIVD provides Uncut sheets, OEM Test kits, Proteins, Analyzers and other products and services for the Fluorescence immunoassay(FIA) technology platform.
AIVD FIA solutions cover the following diseases:cardiac markers, inflammatory markers, hormone markers, tumor markers, stomach's function markers, thyroid markers and others.
Items | Product Name | Catalog NO. | Correlation coefficient | Format |
Cardiac Marker |
Cardiac Troponin-I (cTnl) |
IFCNI001/ IFCNI100 | 0.96 |
Uncut Sheet Test Card |
Myoglobin (Myo) |
IFMYO001/IFMYO100 | 0.93 |
Uncut Sheet Test Card |
|
Creatine kinase-MB (CK-MB) |
IFCKB001/IFCKB100 | 0.93 |
Uncut Sheet Test Card |
|
N-terminal pro hormone BNP (NT-proBNP) |
IFNTP001/IFNTP100 | 0.97 |
Uncut Sheet Test Card |
|
D-Dimer | IFDDT001/IFDDT100 | 0.95 |
Uncut Sheet Test Card |
|
Heart-Type Fatty Acid-Binding Proteins(h-FABP) | IFABP001/IFABP100 | 0.93 |
Uncut Sheet Test Card |
|
cTnl/CK-MB | IFCC001/IFCC100 | Same as single item |
Uncut Sheet Test Card |
|
cTnl/CK-MB/Myo Combo | IFIBO001/IFIBO100 | Same as single item |
Uncut Sheet Test Card |
|
Inflammatory Marker | High-Sensitivity C-Reactive Protein(hSCRP-CRP) | IFCRP001/IFCRP100 | 0.93 |
Uncut Sheet Test Card |
Procalcitonin(PCT) | IFPCT001/IFPCT100 | 0.93 |
Uncut Sheet Test Card |
|
Serum amyloid A(SAA) | IFSAA001/IFSAA100 | 0.95 |
Uncut Sheet Test Card |
|
Interleukin 6(IL-6) | IFIL6001/IFIL6100 | 0.94 |
Uncut Sheet Test Card |
|
CRP/SAA | IFCSA001/IFCSA100 | Same as single item |
Uncut Sheet Test Card |
|
PCT/IL-6 | IFPI6001/IFPI6100 | Same as single item |
Uncut Sheet Test Card |
|
Hormone Marker | Follicle-stimulating hormone(FSH) | IFFSH001/IFFSH100 | 0.93 |
Uncut Sheet Test Card |
Luteinizing hormone(LH) | IFLH001/IFLH100 | 0.96 |
Uncut Sheet Test Card |
|
Progesterone(prog) | IFPRO001/IFPRO100 | 0.90 |
Uncut Sheet Test Card |
|
Prolactin(PRL) | IFPRL001/IFPRL100 | 0.94 |
Uncut Sheet Test Card |
|
Anti-Müllerian hormone (AMH) |
IFAMH001/IFAMH100 | 0.97 |
Uncut Sheet Test Card |
|
Human Chorionic Gonadotrophin (HCG) |
IFHCG001/IFHCG100 | 0.99 |
Uncut Sheet Test Card |
|
Hydrocortisone (COR) |
IFCOR001/IFCOR100 | 0.97 |
Uncut Sheet Test Card |
|
Tumor Marker |
Carcinoembryonic antigen (CEA) |
IFCEA001/IFCEA100 | 0.93 |
Uncut Sheet Test Card |
Alpha fetoprotein (AFP) |
IFAFP001/IFAFP100 | 0.96 |
Uncut Sheet Test Card |
|
Stomach's Function | Pepsinogen 1(PGI) | IFPGI001/IFPGI100 | 0.95 |
Uncut Sheet Test Card |
PepsinogenII(PGII) | IFPGII001/IFPGII100 | 0.94 |
Uncut Sheet Test Card |
|
PGI/PGII | IF2PG001/IF2PG100 | Same as single item |
Uncut Sheet Test Card |
|
Gastrin (G17) | IFG17001/IFG17100 | 0.95 |
Uncut Sheet Test Card |
|
Thyroid Marker | FreeThyroxine(FT4) | IFFT4001/IFFT4100 | 0.98 |
Uncut Sheet Test Card |
Others |
Microalbuminuria (MAU) |
IFMAU001/IFMAU100 | 0.96 |
Uncut Sheet Test Card |
Hemoglobin A1C (HbA1c) |
IFHbA1c001/IFHbA1c100 | 0.91 |
Uncut Sheet Test Card |
|
Ferritin (Fer) | IFFer001/IFFer100 | 0.94 |
Uncut Sheet Test Card |
Typical Product Performance Data:
Benchtop Fluorescence Immunoassay Analyzer:
Product Name: Benchtop Fluorescence Immunoassay Analyzer
Model # : AI-IF 600
Wave length: Excitation wavelength of 365nm, absorption of 610nm. Features: 1.Can be operated in batches rapidly 2.One-click operation, card ejects automatically 3.Identify the test item automatically 4.Automatically print and upload the data 5.High sensitivity, reach to nanogram level |
Our Capabilities
Equipped with the sensitive FIA technology and rich expertise in IVD assay development, AIVD Biotech is confident in offering a flexible FIA-based detection development service. Besides, we also customize a personalized FIA-based testing solution according to your project's requirements. If you are interested in our services, please contact us to discuss your project and achieve more details.
Service Features: |
|
Service Contents: |
1. OEM service for diverse parameters and performance requirements.
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1. Raw materials development and production 2. Optimization of raw material coupling process system 3. Optimization of production process 4. Guidance for production platform and personnel training 5. Production of bulk reagents and uncut sheets 6. Development for new products 7. Technical transfer |
Shenzhen AIVD Biotechnology Co. , LTD.
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E-mail:
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info@aivdbiotech.com
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